Hereditary Hemorrhagic Telangiectasia is primarily associated with which type of anemia?

• A. Pernicious anemia
• B. B12 deficiency
• C. Iron deficiency
• D. Hyperlipidemia

Answer: (C)

Hereditary Hemorrhagic Telangiectasia (HHT), also known as Osler-Weber-Rendu syndrome, is characterized by the development of abnormal blood vessels, leading to an increased risk of bleeding. The presence of these vascular malformations can result in recurrent nosebleeds, gastrointestinal bleeding, and other hemorrhagic complications.

In patients with HHT, chronic bleeding can lead to iron deficiency anemia. This type of anemia occurs when the body does not have enough iron to produce hemoglobin, the protein in red blood cells that carries oxygen. Continuous blood loss from the abnormal blood vessels in HHT can cause a decrease in iron stores in the body, ultimately leading to iron deficiency anemia.

The other types of anemia listed, such as pernicious anemia and B12 deficiency anemia, are primarily related to issues with absorption and metabolism of specific nutrients, rather than direct blood loss. Hyperlipidemia is not an anemia at all; it refers to elevated levels of lipids in the blood and does not relate to the bleeding problems typically seen in HHT. Therefore, recognizing the link between chronic bleeding and iron deficiency is essential in understanding why iron deficiency anemia is the condition most associated with Hereditary Hemorrhagic Telang