Which drug may increase the risk of periodontal destruction due to its side effects?

• A. Ciprofloxacin
• B. Amlodipine
• C. Amoxicillin
• D. Ibuprofen

Answer: (B)

The drug that may increase the risk of periodontal destruction due to its side effects is amlodipine. This medication is a calcium channel blocker commonly used to treat hypertension and angina. One of the noted adverse effects of amlodipine is gingival hyperplasia, which can lead to periodontal issues. Gingival hyperplasia results in the overgrowth of gum tissue, which can create pockets where bacteria thrive, ultimately contributing to periodontal disease if oral hygiene is compromised.

This highlights the importance of monitoring dental health in patients taking amlodipine, as the drug's side effects can directly influence the health of the periodontium. Regular dental check-ups are recommended for patients on this medication to mitigate risks associated with periodontal disease.